Overview
Mood disorders, drug addition and schizophrenia do not have the same cause but they share several underlying factors. All have some genetic component that is not well understood. All involve several regions of the brain. And all are difficult to treat.
Drugs successfully treat some of these schizophrenic and depressed patients but are ineffective for others. They also often have side effects that can make their use less pleasant.
Pay particular attention to incident rates and onset periods. They vary greatly between disorders.
Learning Objectives
By the end of this module, you should be able to:
- Compare and contrast theories of schizophrenia.
- Explain the importance of glutamate in schizophrenia.
- Describe the properties of major depression.
- Describe the reward system and impact of dopamine on drug addition.
Readings
- Kalat C14
- Memory Disorders
- Mood Disorders
- Schizophrenia
- Brain Reward System (5 parts)
Slides
Videos
Review
In preparation for the exam, this is an opportunity to consolidate your knowledge and let your imagination fly. Find a way to summarize the knowledge you’ve gained. You can make a drawing, mind map, term cluster, storyboard, song, slide presentation, flash cards and anything else you can upload. You will be graded on presentation quality (professional looking, not hand written) and thoroughness, not correctness.
Study Aids
Key Terms
- addiction
- affinity
- agonist
- Antabuse
- antagonist
- antipsychotic (neuroleptic) drugs
- atypical antidepressants
- autism spectrum disorder
- bipolar disorder
- butyrophenones
- chlorpromazine
- concordance
- craving
- deep brain stimulation
- defferential diagnosis
- delusions
- DISC1
- dopamine hypothesis of schizophrenia
- efficacy
- electroconvulsive therapy (ECT)
- folic acid
- glutamate hypothesis of schizophrenia
- lithium
- major depression
- mania
- mesolimbocortical system
- methadone
- monoamine oxidase inhibitors (MAOIs)
- negative symptoms
- neurodevelopmental hypothesis
- nucleus accumbens
- phencyclidine (PCP)
- phenothiazines
- positive symptoms
- schizophrenia
- season-of-birth effect
- seasonal affective disorder (SAD)
- second-generation antipsychotics
- selective serotonin reuptake inhibitors (SSRIs)
- self-stimulation of the brain
- serotonin norepinephrine reuptake inhibitor (SNRIs)
- substance-induced psychotic disorder
- tardive dyskinesia
- tolerance
- tricyclics
- Type I (Type A) alcoholism
- Type II (Type B) alcoholism
- withdrawal
Links
- Neuroscience for Kids: Schizophrenia (Links to an external site.)
- Neuroscience for Kids: Bipolar Disorder (Links to an external site.)
Summary
Panic attacks, schizophrenia, depression and autism are among the challenges people fact that have both genetic and environmental causes.